Mechanistic Theories of Life, Sensation & Consciousness
Exploring the leading scientific theories for the origins of life's most fundamental phenomena
Chemical Origin of Life
Abiogenesis & Systems Chemistry
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RNA World HypothesisSelf-replicating RNA molecules as both genetic material and catalysts
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Metabolism-First HypothesesAutocatalytic metabolic networks preceded genetic systems
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Hybrid ModelsCombining replication and metabolism for mutual reinforcement
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CompartmentalizationFormation of protocells via lipid membranes for concentration and protection
Origin of Sensation
From Responsiveness to Perception
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Evolution of Sensory MechanismsPrimitive cells developed receptors for environmental stimuli
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Connection to MetabolismEarly metabolic networks integrated sensory functions
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Neurobiological PerspectivesSpecialized neurons and neural circuits for sensation
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Global Neuronal Workspace TheorySensory information becomes conscious when broadcast globally
Origin of Consciousness
Emergence from Neural Complexity
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Integrated Information Theory (IIT)Consciousness corresponds to integrated information in neural networks
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Global Neuronal Workspace Theory (GNWT)Consciousness emerges when information is distributed across cortical regions
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Electromagnetic TheoriesBrain EM fields unify neural information, solving the "binding problem"
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Biochemical BasisNeurotransmitters, ion channels, and neural oscillations critical for consciousness
Key Interconnected Concepts
Dynamic Kinetic Stability (DKS)
Systems that efficiently replicate and evolve are favored, driving complexity
Autocatalysis
Self-amplifying reactions leading to exponential growth of molecules
Continuity from Chemistry to Consciousness
Abiogenesis and biological evolution as part of a continuous process
The Hard Problem
Why and how subjective experience arises from physical processes
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